Description

5-Trifluoromethyl-Pyrimidin-4-Ylamine is a high-value fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique reactivity and electronic properties imparted by the trifluoromethyl and amine functional groups on the pyrimidine scaffold. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science: Potential monomer or functionalizing agent for creating specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Versatile reagent for constructing complex heterocyclic systems in medicinal and process chemistry.
• Life Science Research: Employed as a biochemical probe or tool compound in academic and industrial R&D for target validation and mechanism studies.

Basic Information

Product Name	5-Trifluoromethyl-Pyrimidin-4-Ylamine
CAS No.	1805131-89-8
Molecular Formula	C5H4F3N3
Molecular Weight	163.10 g/mol
Synonyms	4-Amino-5-(trifluoromethyl)pyrimidine; 5-(Trifluoromethyl)pyrimidin-4-amine; 4-Pyrimidinamine, 5-(trifluoromethyl)-; 5-Trifluoromethyl-4-pyrimidinamine; 5-Trifluoromethyl-4-aminopyrimidine; 4-Amino-5-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethyl-Pyrimidin-4-Ylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.