Description

4-Bromo-2-Fluoro-3-Hydroxybenzaldehyde is a high-purity, multi-functional aromatic aldehyde derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and hydroxylated structure makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the bromo and fluoro substituents can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) precursors and liquid crystals, due to its electron-withdrawing and donating functional groups.
• Fluorescent Probe and Dye Chemistry: Acts as a core structure for developing fluorescent tags, sensors, and specialized dyes used in bio-imaging and analytical chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity halogenated benzaldehyde derivatives.

Basic Information

Product Name	4-Bromo-2-Fluoro-3-Hydroxybenzaldehyde
CAS No.	1805027-41-1
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	3-Hydroxy-4-bromo-2-fluorobenzaldehyde; 2-Fluoro-3-hydroxy-4-bromobenzaldehyde; 4-Bromo-2-fluoro-3-hydroxybenzenecarboxaldehyde; 4-Bromo-2-fluoro-3-hydroxy-benzaldehyde; Benzaldehyde, 4-bromo-2-fluoro-3-hydroxy-
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluoro-3-Hydroxybenzaldehyde is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.