Description

Pyrimidine, 4-[5-Chloro-2-[4-(Trimethylsilyl)-1H-1,2,3-Triazol-1-Yl]Phenyl]-6-Methoxy- is a high-value, functionalized heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, combining pyrimidine, triazole, and silyl-protected functional groups, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty materials. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and cellular pathways.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	Pyrimidine, 4-[5-Chloro-2-[4-(Trimethylsilyl)-1H-1,2,3-Triazol-1-Yl]Phenyl]-6-Methoxy-
CAS No.	1802430-53-0
Molecular Formula	C16H18ClN5OSi
Molecular Weight	375.88 g/mol
Synonyms	4-(5-Chloro-2-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)phenyl)-6-methoxypyrimidine; 6-Methoxy-4-[5-chloro-2-[4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl]phenyl]pyrimidine; 1802430-53-0; 4-(5-Chloro-2-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)phenyl)-6-methoxy-pyrimidine; TMS-Triazole Pyrimidine Derivative; 1-(5-Chloro-2-(6-methoxypyrimidin-4-yl)phenyl)-4-(trimethylsilyl)-1H-1,2,3-triazole
EINECS	Contact for details

Quality Control

Every batch of Pyrimidine, 4-[5-Chloro-2-[4-(Trimethylsilyl)-1H-1,2,3-Triazol-1-Yl]Phenyl]-6-Methoxy- is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.