Description

Glp-1 (7-36)-Lys(6-Fam) Amide (Human, Bovine, Guinea Pig, Mouse, Rat) is a fluorescently labeled analog of the Glucagon-like Peptide-1 (GLP-1) hormone, specifically designed for advanced research applications. This compound is critical for studying GLP-1 receptor binding, internalization, and trafficking dynamics in live-cell imaging and fluorescence-based assays. It is an essential tool for pharmaceutical R&D and academic researchers focused on diabetes, obesity, and metabolic disease pathways across multiple species models.

Application

• Fluorescence Microscopy & Live-Cell Imaging: Visualizing real-time GLP-1 receptor interaction and localization in various cell lines.
• Receptor Binding & Competition Assays: Quantifying binding affinity and kinetics for GLP-1 receptor ligands.
• Drug Discovery Screening: High-throughput screening (HTS) for novel GLP-1 receptor agonists and antagonists.
• Internalization & Trafficking Studies: Tracking the cellular uptake and intracellular pathway of the GLP-1 receptor complex.
• Biophysical Characterization: Utilizing fluorescence anisotropy (FP) or FRET-based techniques for molecular interaction analysis.
• Comparative Pharmacology Research: Enabling cross-species studies in human, bovine, guinea pig, mouse, and rat models.

Basic Information

Product Name	Glp-1 (7-36)-Lys(6-Fam) Amide (Human, Bovine, Guinea Pig, Mouse, Rat)
CAS No.	1802089-53-7
Molecular Formula	C198H284N48O61S
Molecular Weight	4266.7 g/mol
Synonyms	GLP-1 (7-36) amide, FAM-labeled; Fluorescein-GLP-1(7-36)amide; Glucagon-like peptide 1 (7-36) amide, 6-FAM conjugate; 6-Carboxyfluorescein-GLP-1(7-36)amide; FAM-GLP-1(7-36)NH2; GLP-1 Fluorescent Tracer; GLP-1 Receptor Fluorescent Ligand; Lyophilized GLP-1 analog
EINECS	Contact for details

Quality Control

Every batch of Glp-1 (7-36)-Lys(6-Fam) Amide is manufactured and analyzed under strict quality protocols to ensure the highest standards of purity and performance for research use. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and fluorescence properties are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Extinction Coefficient (ε)	~68,000 cm-1M-1 at 494 nm
Fluorescence Emission	~518 nm
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.