Description

H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Lys(Biotinyl)-NH2 is a synthetic, biotinylated peptide sequence designed for advanced research and development applications. This compound is critical for studies involving protein-protein interactions, affinity purification, and signal transduction pathways due to its high-affinity binding to streptavidin. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic research, drug discovery, and diagnostic assay development.

Application

• Biochemical Research: Used as a high-affinity probe or tag in studying hormone receptors, enzyme kinetics, and intracellular signaling mechanisms.
• Diagnostic Development: Serves as a key component in the development of ELISA, lateral flow assays, and other immunoassays for biomarker detection.
• Drug Discovery: Employed in high-throughput screening (HTS) platforms and as a targeting moiety in the design of novel bioconjugates and therapeutic agents.
• Affinity Purification: Facilitates the isolation and purification of specific proteins or complexes using streptavidin/avidin-biotin technology.
• Cell Biology Studies: Used to label, track, or immobilize biomolecules in live-cell imaging and flow cytometry applications.
• Proteomics & Genomics: Acts as a tool in pull-down assays, microarray fabrication, and next-generation sequencing library preparation.

Basic Information

Product Name	H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Lys(Biotinyl)-NH2
CAS No.	1802086-70-9
Molecular Formula	C155H238N44O47S
Molecular Weight	3418.9 g/mol
Synonyms	Biotinylated GLP-1 (7-36) amide analog; Biotin-GLP-1 peptide; Lys(Biotin)-GLP-1; Biotinylated Glucagon-like peptide-1 fragment; Biotin-HH-AEGTFTSDVSSYLEGQAAKEFIAWLVKGRK-NH2; GLP-1 (7-36) amide, Biotinylated; Biotin-labeled GLP-1; Research peptide 1802086-70-9
EINECS	Contact for details

Quality Control

Every batch of our biotinylated peptides is manufactured under GMP-like conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Standard quality control includes HPLC for purity assessment, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and biotin incorporation ratio is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. Aliquot into single-use vials after reconstitution to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Biotin Incorporation	≥ 95% (by HPLC/ELISA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.