Description

([D8]Val7,10)-C-Peptide (Human) is a stable isotope-labeled analog of the human C-peptide, a critical biomarker for endogenous insulin production. This deuterated compound is essential for providing an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reproducibility in clinical and research assays. It is primarily required by pharmaceutical R&D laboratories, clinical diagnostics developers, and academic researchers focused on diabetes research and metabolic studies.

Application

• Quantitative Mass Spectrometry (LC-MS/MS): Serves as a critical internal standard for the precise and accurate quantification of endogenous C-peptide in biological matrices like serum and plasma.
• Clinical Diagnostics Development: Used in the development and validation of high-sensitivity immunoassays and MS-based clinical tests for diabetes management and pancreatic function assessment.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables reliable tracking of synthetic C-peptide or insulin analogs in pre-clinical and clinical research.
• Biomarker Research: Facilitates discovery and validation studies for metabolic disorders by providing a stable reference point in complex sample analysis.
• Quality Control in Manufacturing: Acts as a reference material in the quality control of therapeutic peptides and related diagnostic kits.

Basic Information

Product Name	([D8]Val7,10)-C-Peptide (Human)
CAS No.	1802078-41-6
Molecular Formula	C112H168D8N24O32
Molecular Weight	~ 2458.8 g/mol (monoisotopic)
Synonyms	Deuterated C-Peptide (Human); [D8]Val7,10 Human C-Peptide; C-Peptide (Human), [Val-7,10-d8]; Stable Isotope-Labeled C-Peptide; Proinsulin C-Peptide (Human) deuterated; Internal Standard for C-Peptide Quantification; IS for C-Peptide MS; CPEP-d8
EINECS	Contact for details

Quality Control

Our ([D8]Val7,10)-C-Peptide (Human) is manufactured under strict quality systems suitable for research and diagnostic use. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for isotopic enrichment verification, to ensure consistent performance as a mass spectrometry internal standard. Certificates of Analysis (COA) detailing purity, isotopic purity, and analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Isotopic Purity (Enrichment)	≥ 98 atom % D
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.