Description

(Des-Thr7)-Glucagon CAS NO 1802078-28-9 is a synthetic peptide analog of the glucagon hormone, specifically engineered for research and development purposes. This compound is of significant value for its role in studying glucagon receptor activity, metabolic pathways, and the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on endocrinology, diabetes, and metabolic disease research.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of glucagon receptor binding and signal transduction mechanisms.
• Drug Discovery: Serves as a key intermediate or lead compound in the development of new glucagon receptor modulators for metabolic disorders.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays and test kits designed to measure glucagon or related peptides.
• Metabolic Studies: Applied in cellular and animal models to investigate the physiological effects of glucagon and its analogs on glucose metabolism.
• Peptide Chemistry: Utilized as a building block or model compound in peptide synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	(Des-Thr7)-Glucagon
CAS No.	1802078-28-9
Molecular Formula	C152H226N42O48S
Molecular Weight	~3484.8 g/mol
Synonyms	Des-Threonine7-Glucagon; Glucagon (1-29) (human, bovine, porcine), 7-de-L-threonine; [Des-Thr7]-Glucagon; Glucagon (7-de-Thr); H-His-Ser-Gln-Gly-Thr-Phe-Asp-Ser-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH; Glucagon fragment 1-29 (7-de-Thr)
EINECS	Contact for details

Quality Control

Our (Des-Thr7)-Glucagon is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.