Description

3-Chloro-4-Fluoro-5-Nitrophenol is a high-purity, multi-functional halogenated nitrophenol derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique substitution pattern makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, pesticides, and fungicides, leveraging its phenolic and nitro functionalities.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, dyes, and pigments.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and as a scaffold for further chemical modifications in academic and industrial R&D.
• Ligand and Catalyst Development: Useful for creating novel chelating ligands in coordination chemistry and catalysis research.

Basic Information

Product Name	3-Chloro-4-Fluoro-5-Nitrophenol
CAS No.	1799412-26-2
Molecular Formula	C6H3ClFNO3
Molecular Weight	191.54 g/mol
Synonyms	5-Nitro-3-chloro-4-fluorophenol; 3-Chloro-4-fluoro-5-nitro-1-hydroxybenzene; Phenol, 3-chloro-4-fluoro-5-nitro-; 1-Hydroxy-3-chloro-4-fluoro-5-nitrobenzene; 4-Fluoro-3-chloro-5-nitrophenol
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluoro-5-Nitrophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and spectroscopic identification (IR, NMR), to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.