Description

tert-Butyl 4-(2-Chloropyrimidin-4-Yl)-2-Methylbenzylcarbamate is a high-purity chemical intermediate of significant importance in modern pharmaceutical research and development. This compound matters because it serves as a critical building block for the synthesis of more complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. Pharmaceutical companies, contract research organizations (CROs), and advanced fine chemical manufacturers need this material for its role in creating novel therapeutic agents targeting various diseases.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors and other small-molecule drug candidates.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research & Development (R&D): Essential for academic and industrial research focused on oncology, immunology, and metabolic disorder therapeutics.
• Process Chemistry: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: Serves as a starting material for contract manufacturing organizations (CMOs) producing specialized compounds for clients.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	tert-Butyl 4-(2-Chloropyrimidin-4-Yl)-2-Methylbenzylcarbamate
CAS No.	1798791-44-2
Molecular Formula	C17H20ClN3O2
Molecular Weight	333.81 g/mol
Synonyms	Boc-4-(2-Chloropyrimidin-4-yl)-2-methylbenzylamine; tert-Butyl N-[4-(2-chloropyrimidin-4-yl)-2-methylbenzyl]carbamate; 4-(2-Chloropyrimidin-4-yl)-2-methylbenzylcarbamic Acid tert-Butyl Ester; 2-Methyl-4-(2-chloropyrimidin-4-yl)benzyl Carbamic Acid tert-Butyl Ester; 1798791-44-2; tert-Butyl (4-(2-chloropyrimidin-4-yl)-2-methylbenzyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Chloropyrimidin-4-Yl)-2-Methylbenzylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.