Description

4-Amino-1-tert-Butyl-3-(2-Methoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for developing selective enzyme modulators in biochemical assays.
• API Development: Employed in the process development and scale-up of active pharmaceutical ingredients (APIs) with pyrazolopyrimidine cores.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	4-Amino-1-tert-Butyl-3-(2-Methoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	1797105-85-1
Molecular Formula	C₁₇H₂₁N₅O
Molecular Weight	311.38 g/mol
Synonyms	4-Amino-1-(tert-butyl)-3-(2-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 4-amino-1-(1,1-dimethylethyl)-3-(2-methoxyphenyl)-; 4-Amino-1-tert-butyl-3-(o-methoxyphenyl)pyrazolo[3,4-d]pyrimidine; 1797105-85-1; ATBMPP; tert-Butyl Pyrazolopyrimidine Amine Derivative
EINECS	Contact for details

Quality Control

Our 4-Amino-1-tert-Butyl-3-(2-Methoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete batch data are provided to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.