Description

Methyl 2-(Aminomethyl)Pyrimidine-5-Carboxylate Hydrochloride is a high-purity pyrimidine derivative, serving as a critical building block in modern organic synthesis. Its value lies in its functionalized structure, which provides a versatile scaffold for constructing complex molecules with pharmaceutical relevance. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive pyrimidine core.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Bioconjugate Chemistry: The aminomethyl group facilitates conjugation reactions for creating labeled probes or drug-linker complexes.
• Academic & Contract Research: Serves as a valuable reagent for synthetic methodology development and novel compound library generation in R&D laboratories.

Basic Information

Item	Detail
Product Name	Methyl 2-(Aminomethyl)Pyrimidine-5-Carboxylate Hydrochloride
CAS No.	1788041-60-0
Molecular Formula	C8H12ClN3O2
Molecular Weight	217.65 g/mol
Synonyms	2-(Aminomethyl)pyrimidine-5-carboxylic acid methyl ester hydrochloride; Methyl 5-(aminomethyl)pyrimidine-2-carboxylate hydrochloride; 5-(Methoxycarbonyl)pyrimidine-2-methylamine hydrochloride; 2-Carbomethoxy-5-aminomethylpyrimidine hydrochloride; 2-(Aminomethyl)-5-(methoxycarbonyl)pyrimidine HCl; Pyrimidine-5-carboxylic acid, 2-(aminomethyl)-, methyl ester, hydrochloride; MA5PCH
EINECS	Contact for details

Quality Control

Our Methyl 2-(Aminomethyl)Pyrimidine-5-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.