Description

2-Bromo-3,4,6-Trifluoro-Phenol is a halogenated phenol derivative with a unique trifluoromethyl substitution pattern, serving as a versatile and high-value fluorinated building block. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling the development of advanced materials and active ingredients. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for synthesizing novel compounds with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and pesticides, where the fluorine atoms improve lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic display materials, enhancing charge transport and thermal stability.
• Polymer Modification: Employed to introduce fluorine into polymer backbones or side chains, improving chemical resistance, lowering surface energy, and enhancing material performance.
• Organic Synthesis & Catalysis: Acts as a specialized reagent or ligand precursor in cross-coupling reactions and catalytic cycles for complex molecule construction.
• Academic & Contract Research: Essential for fundamental research in fluorine chemistry and for contract research organizations (CROs) developing custom synthetic routes.

Basic Information

Product Name	2-Bromo-3,4,6-Trifluoro-Phenol
CAS No.	1785516-22-4
Molecular Formula	C6H2BrF3O
Molecular Weight	224.98 g/mol
Synonyms	2-Bromo-3,4,6-trifluorophenol; 3,4,6-Trifluoro-2-bromophenol; Phenol, 2-bromo-3,4,6-trifluoro-; 2-Bromo-3,4,6-trifluoro-1-hydroxybenzene; 1-Bromo-2,3,5-trifluoro-6-hydroxybenzene; 2-Bromo-3,4,6-trifluorobenzenol; TFBP (common abbreviation)
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-3,4,6-Trifluoro-Phenol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.