Description

(5-Chloro-4-Fluoro-2-Methoxy-Phenyl)-Methanol is a versatile fluorinated and chlorinated benzyl alcohol derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized aromatic scaffold with multiple points for selective chemical modification, enabling the synthesis of complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides that leverage its halogenated aromatic structure for enhanced bioactivity.
• Liquid Crystal & OLED Material Research: Used in the development of fluorinated organic electronic materials for displays and lighting applications.
• Chiral Ligand & Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for fine chemical companies offering bespoke synthesis services.
• Academic & R&D Laboratories: Employed in methodological studies and the exploration of new fluorination and functionalization reactions.

Basic Information

Product Name	(5-Chloro-4-Fluoro-2-Methoxy-Phenyl)-Methanol
CAS No.	1785513-46-3
Molecular Formula	C8H8ClFO2
Molecular Weight	190.60 g/mol
Synonyms	(5-Chloro-4-fluoro-2-methoxyphenyl)methanol; 5-Chloro-4-fluoro-2-methoxybenzenemethanol; 2-Methoxy-5-chloro-4-fluorobenzyl alcohol; 1-(5-Chloro-4-fluoro-2-methoxyphenyl)methanol; Benzenemethanol, 5-chloro-4-fluoro-2-methoxy-; CAS 1785513-46-3
EINECS	Contact for details

Quality Control

Every batch of (5-Chloro-4-Fluoro-2-Methoxy-Phenyl)-Methanol is produced under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with ICH guidelines and can tailor specifications to meet specific project requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.