Description

4-Fluoro-3-Methoxy-5-Methylbenzaldehyde is a high-purity aromatic aldehyde building block of significant interest in advanced organic synthesis. Its unique substitution pattern, featuring fluorine, methoxy, and methyl groups, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic materials used in displays and organic light-emitting diodes.
• Functional Dye & Pigment Chemistry: Employed in the creation of specialized dyes and pigments where the aldehyde group allows for further condensation and chromophore extension.
• Cross-Coupling Reactions: The aldehyde and halogen functionalities make it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to build biaryl systems.
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new chemical spaces and synthesizing libraries of compounds for screening.

Basic Information

Product Name	4-Fluoro-3-Methoxy-5-Methylbenzaldehyde
CAS No.	1785229-80-2
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	5-Methyl-3-methoxy-4-fluorobenzaldehyde; 4-Fluoro-3-methoxy-5-methyl-benzaldehyde; 3-Methoxy-4-fluoro-5-methylbenzaldehyde; Benzaldehyde, 4-fluoro-3-methoxy-5-methyl-; 5-Methyl-4-fluoro-3-methoxybenzaldehyde; 4-Fluoro-5-methyl-3-methoxybenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3-Methoxy-5-Methylbenzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.