Description

1,2,2-Trifluorocyclohexanecarboxylic Acid is a high-value fluorinated carboxylic acid building block, prized for its unique structural features that enable the fine-tuning of molecular properties. This compound is essential for advanced research and development, particularly in the creation of novel active ingredients with enhanced metabolic stability and bioavailability. It is a critical intermediate for pharmaceutical chemists and agrochemical researchers focused on next-generation drug discovery and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Research: Used to develop novel herbicides and pesticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique chemical resistance and surface properties.
• Organic Synthesis Building Block: Utilized in medicinal and combinatorial chemistry for constructing complex, fluorinated molecular scaffolds.
• Fluorine-19 NMR Spectroscopy: Can be used as a reference compound or probe in analytical chemistry and biochemical studies.

Basic Information

Product Name	1,2,2-Trifluorocyclohexanecarboxylic Acid
CAS No.	1784919-58-9
Molecular Formula	C7H9F3O2
Molecular Weight	182.14 g/mol
Synonyms	Cyclohexanecarboxylic acid, 1,2,2-trifluoro-; 1,2,2-Trifluorocyclohexane-1-carboxylic acid; 2,2,3-Trifluorocyclohexanecarboxylic acid; 1-Carboxy-1,2,2-trifluorocyclohexane; Trifluorocyclohexanecarboxylic acid; 1784919-58-9; 1,2,2-Trifluorocyclohexanecarboxylic acid (CAS 1784919-58-9)
EINECS	Contact for details

Quality Control

Our production of 1,2,2-Trifluorocyclohexanecarboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and heat sources. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.