Description

3-Bromo-2-Chloro-6-Fluorobenzyl Alcohol is a high-purity, multi-halogenated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the halogen atoms contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in both university and corporate research laboratories.

Basic Information

Product Name	3-Bromo-2-Chloro-6-Fluorobenzyl Alcohol
CAS No.	1784628-56-3
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	(3-Bromo-2-chloro-6-fluorophenyl)methanol; 2-Chloro-3-bromo-6-fluorobenzyl alcohol; 6-Fluoro-3-bromo-2-chlorobenzyl alcohol; 1-(Bromochlorodifluoromethyl)benzene-3-ol (incorrect but sometimes listed); Benzyl alcohol, 3-bromo-2-chloro-6-fluoro-; BCFBA (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Chloro-6-Fluorobenzyl Alcohol is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.