Description

5-Bromo-2-Chloro-4-Fluorobenzaldehyde is a high-purity halogenated benzaldehyde derivative serving as a critical building block in advanced organic synthesis. Its multi-halogenated aromatic structure makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the halogen substituents for bioactivity.
• Ligand and Catalyst Development: Used to prepare specialized ligands for transition metal catalysis and organocatalysts in asymmetric synthesis.
• Material Science Research: Intermediate in the production of organic electronic materials, such as OLED (Organic Light-Emitting Diode) precursors and liquid crystals.
• Custom Chemical Synthesis: Serves as a versatile starting material for contract research organizations (CROs) and CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.
• Fluorine Chemistry Studies: Valuable substrate for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal chemistry.

Basic Information

Item	Details
Product Name	5-Bromo-2-Chloro-4-Fluorobenzaldehyde
CAS No.	1782815-29-5
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	2-Chloro-5-bromo-4-fluorobenzaldehyde; 4-Fluoro-2-chloro-5-bromobenzaldehyde; 5-Bromo-2-chloro-4-fluorobenzenecarboxaldehyde; Benzaldehyde, 5-bromo-2-chloro-4-fluoro-; (5-Bromo-2-chloro-4-fluorophenyl)methanal
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4-Fluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.