Description

tert-Butyl 2-Chloro-4-Methyl-5H,6H,7H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyrimidine class of heterocyclic compounds. Its core value lies in serving as a critical building block for the synthesis of complex, biologically active molecules, particularly in medicinal chemistry and drug discovery. This compound is essential for research and development chemists in the pharmaceutical and biotechnology industries who are developing novel therapeutic agents, such as kinase inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially those targeting protein kinases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and selectivity.
• Biochemical Tool Compound: Serves as a scaffold or starting material for creating probes used in biochemical and cellular assays to study disease pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	tert-Butyl 2-Chloro-4-Methyl-5H,6H,7H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylate
CAS No.	1781872-15-8
Molecular Formula	C12H16ClN3O2
Molecular Weight	269.73 g/mol
Synonyms	2-Chloro-4-methyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester; tert-Butyl 2-chloro-4-methyl-5,8-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate; 6-(tert-Butoxycarbonyl)-2-chloro-4-methyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine; 2-Chloro-4-methyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid 1,1-dimethylethyl ester; BOC-protected 2-chloro-4-methyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Chloro-4-Methyl-5H,6H,7H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.