Description

3-(1,1-Difluoroethyl)-α,α-Dimethyl- Benzenemethanol is a specialized fluorinated aromatic alcohol building block. This compound is valued for its unique structure, which incorporates a difluoroethyl group adjacent to a benzylic alcohol, making it a versatile intermediate for introducing fluorinated motifs into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where the fluorine atoms can significantly alter biological activity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where fluorination enhances compound efficacy and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with tailored surface properties.
• Liquid Crystal & OLED Materials: Potential intermediate for creating fluorinated components in electronic display materials and organic light-emitting diodes.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector with complex, fluorinated organic molecules.

Basic Information

Product Name	3-(1,1-Difluoroethyl)-α,α-Dimethyl- Benzenemethanol
CAS No.	1780914-12-6
Molecular Formula	C11H14F2O
Molecular Weight	200.23 g/mol
Synonyms	α,α-Dimethyl-3-(1,1-difluoroethyl)benzenemethanol; 1-[3-(1,1-Difluoroethyl)phenyl]-2-methylpropan-2-ol; Benzenemethanol, 3-(1,1-difluoroethyl)-α,α-dimethyl-; 3-(1,1-Difluoroethyl)-α,α-dimethylbenzyl Alcohol; (3-(1,1-Difluoroethyl)phenyl)dimethylmethanol
EINECS	Contact for details

Quality Control

Our 3-(1,1-Difluoroethyl)-α,α-Dimethyl- Benzenemethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.