Description

(1-(Difluoromethyl)Cyclobutyl)Methanol is a specialized fluorinated building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoromethyl group adjacent to the cyclobutyl methanol scaffold, enabling precise structural modifications. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis, leveraging the steric profile of the cyclobutyl ring.
• Material Science Research: Employed in the synthesis of fluorinated polymers or specialty chemicals with tailored surface properties and resistance.
• Fluorine Chemistry Exploration: Acts as a valuable substrate for studying novel fluorination reactions and the behavior of difluoromethyl groups in various chemical environments.

Basic Information

Product Name	(1-(Difluoromethyl)Cyclobutyl)Methanol
CAS No.	1780499-30-0
Molecular Formula	C6H10F2O
Molecular Weight	136.14 g/mol
Synonyms	1-(Difluoromethyl)cyclobutane-1-methanol; (1-(Difluoromethyl)cyclobutyl)methanol; α-(Difluoromethyl)cyclobutanemethanol; Cyclobutanemethanol, 1-(difluoromethyl)-; 1-(Difluoromethyl)-1-(hydroxymethyl)cyclobutane
EINECS	Contact for details

Quality Control

Our (1-(Difluoromethyl)Cyclobutyl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.