Description

2-Methanesulfonyl-6-(Trifluoromethyl)Pyrimidin-4-Ol CAS NO 1779983-09-3 is a high-value, multi-functional pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a methanesulfonyl and a trifluoromethyl group, makes it an essential intermediate for creating compounds with tailored biological and physical properties. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of chemical probes and affinity tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-Methanesulfonyl-6-(Trifluoromethyl)Pyrimidin-4-Ol
CAS No.	1779983-09-3
Molecular Formula	C6H5F3N2O3S
Molecular Weight	242.18 g/mol
Synonyms	6-(Trifluoromethyl)-2-(methylsulfonyl)pyrimidin-4-ol; 4-Hydroxy-6-(trifluoromethyl)-2-(methylsulfonyl)pyrimidine; 2-(Methylsulfonyl)-6-(trifluoromethyl)pyrimidin-4-ol; 2-Methanesulfonyl-6-trifluoromethylpyrimidin-4-ol; 4-Pyrimidinol, 6-(trifluoromethyl)-2-(methylsulfonyl)-; 1779983-09-3
EINECS	Contact for details

Quality Control

Our 2-Methanesulfonyl-6-(Trifluoromethyl)Pyrimidin-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production facilities and processes are designed to meet the stringent requirements of cGMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.