Description

5-Methyl-4-(Piperidin-3-yloxy)pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct pyrimidine-piperidine hybrid structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel drug candidates for oncology, neurology, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and biological activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	5-Methyl-4-(Piperidin-3-yloxy)pyrimidine Hydrochloride
CAS No.	1779133-07-1
Molecular Formula	C10H16ClN3O
Molecular Weight	229.71 g/mol
Synonyms	5-Methyl-4-(3-piperidinyloxy)pyrimidine hydrochloride; 4-((Piperidin-3-yl)oxy)-5-methylpyrimidine hydrochloride; 5-Methyl-4-(piperidin-3-yloxy)pyrimidine HCl; 1779133-07-1; UNII-9F6J8L3V4K; 9F6J8L3V4K; 4-(3-Piperidyloxy)-5-methylpyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Methyl-4-(Piperidin-3-yloxy)pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.