Description

7-Iodopyrrolo[2,1-F][1,2,4]Triazin-4-Amine is a high-value, heterocyclic organic building block with significant potential in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, drug discovery, and material science. The precise functionalization offered by this iodinated triazine derivative enables targeted modifications critical for optimizing biological activity and material properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive iodine site for further coupling.
• Material Science: Acts as a precursor for creating functionalized polymers or organic electronic materials with tailored properties.
• Chemical Biology: Employed in the design of molecular probes and labeled compounds for studying biological pathways and mechanisms.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	7-Iodopyrrolo[2,1-F][1,2,4]Triazin-4-Amine
CAS No.	1770840-43-1
Molecular Formula	C6H4IN5
Molecular Weight	273.03 g/mol
Synonyms	7-Iodo-4-aminopyrrolo[2,1-f][1,2,4]triazine; 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine; Pyrrolo[2,1-f][1,2,4]triazin-4-amine, 7-iodo-; 7-Iodo-pyrrolo[2,1-f][1,2,4]triazin-4-ylamine; CAS 1770840-43-1
EINECS	Contact for details

Quality Control

Our 7-Iodopyrrolo[2,1-F][1,2,4]Triazin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.