Description

5-Methyl-4-(Pyrrolidin-3-Yloxy)Pyrimidine Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant interest in modern drug discovery. This compound is valued for its unique heterocyclic structure, which is crucial for the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Oncology Research: Used in the design and synthesis of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Serves as a core scaffold for developing compounds aimed at neurological and psychiatric disorders.
• Chemical Biology: Employed as a probe or tool compound for studying enzyme function and protein-ligand interactions.
• Process Chemistry & Scale-Up: Suitable for use in route scouting and optimization for the commercial manufacturing of candidate drugs.
• Custom Synthesis: A starting material for the preparation of more complex, proprietary molecules under contract research and manufacturing (CRAM) agreements.

Basic Information

Product Name	5-Methyl-4-(Pyrrolidin-3-Yloxy)Pyrimidine Hydrochloride
CAS No.	1713163-97-3
Molecular Formula	C9H14ClN3O
Molecular Weight	215.68 g/mol
Synonyms	4-((3-Pyrrolidinyl)oxy)-5-methylpyrimidine hydrochloride; 5-Methyl-4-(3-pyrrolidinyloxy)pyrimidine HCl; 4-(Pyrrolidin-3-yloxy)-5-methylpyrimidine hydrochloride; 1713163-97-3; 5-Methyl-4-(pyrrolidin-3-yloxy)pyrimidine HCl salt; 5-Methyl-4-[(3-pyrrolidinyl)oxy]pyrimidine monohydrochloride
EINECS	Contact for details

Quality Control

Our 5-Methyl-4-(Pyrrolidin-3-Yloxy)Pyrimidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.