Description

2-(4-Methylpiperazin-1-Yl)Pyrimidine-5-Carbonitrile is a high-value, nitrogen-rich heterocyclic building block with significant utility in advanced organic synthesis. Its core value lies in its bifunctional pyrimidine-carbonitrile scaffold, which serves as a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), particularly kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or precursor for functional polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial research for constructing complex pyrimidine and piperazine derivatives via cross-coupling and cyclization reactions.
• Ligand Synthesis: Useful for preparing chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	2-(4-Methylpiperazin-1-Yl)Pyrimidine-5-Carbonitrile
CAS No.	1710203-01-2
Molecular Formula	C10H12N6
Molecular Weight	216.25 g/mol
Synonyms	2-(4-Methyl-1-piperazinyl)-5-pyrimidinecarbonitrile; 5-Cyano-2-(4-methylpiperazin-1-yl)pyrimidine; 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonitrile; Pyrimidine-5-carbonitrile, 2-(4-methyl-1-piperazinyl)-; 1710203-01-2
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperazin-1-Yl)Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.