Description

1-Bromo-3-[1-(Trifluoromethyl)Cyclopropyl]Benzene is a high-value, multi-functional aromatic building block characterized by its bromine substituent and unique trifluoromethylcyclopropyl group. This compound is essential for introducing sterically hindered, fluorinated motifs into molecular frameworks, which is critical for modulating the physicochemical properties of advanced materials and active pharmaceutical ingredients. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases, where the trifluoromethyl group enhances metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in developing next-generation herbicides, fungicides, and insecticides, where the cyclopropyl and fluorine atoms contribute to improved biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), where its structure helps fine-tune electronic properties and thermal stability.
• Cross-Coupling Reactions: The aryl bromide moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl and conjugated systems.
• Material Science Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and metal-organic frameworks (MOFs) with tailored properties.
• Fluorine Chemistry Studies: A valuable reagent for investigating structure-activity relationships (SAR) and the effects of fluorinated cyclopropanes in medicinal and materials chemistry.

Basic Information

Product Name	1-Bromo-3-[1-(Trifluoromethyl)Cyclopropyl]Benzene
CAS No.	1707572-80-2
Molecular Formula	C10H8BrF3
Molecular Weight	265.07 g/mol
Synonyms	3-Bromo-1-[1-(trifluoromethyl)cyclopropyl]benzene; 1-Bromo-3-(1-(trifluoromethyl)cyclopropyl)benzene; [1-(3-Bromophenyl)cyclopropyl]-trifluoromethane; m-Bromo-(α,α,α-trifluoro-cyclopropyl)benzene; 3-Bromophenyl(trifluoromethyl)cyclopropane; Benzene, 1-bromo-3-[1-(trifluoromethyl)cyclopropyl]-; 1707572-80-2
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-3-[1-(Trifluoromethyl)Cyclopropyl]Benzene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.