Description

4-(2-Methyl-1H-Imidazol-1-Yl)-6-(Piperazin-1-Yl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard or a probe compound in enzymatic assays and target validation studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for chemical biology and novel synthetic methodology development.

Basic Information

Product Name	4-(2-Methyl-1H-Imidazol-1-Yl)-6-(Piperazin-1-Yl)Pyrimidine
CAS No.	1706446-94-7
Molecular Formula	C12H15N7
Molecular Weight	257.30 g/mol
Synonyms	4-(2-Methyl-1H-imidazol-1-yl)-6-(piperazin-1-yl)pyrimidine; 6-(Piperazin-1-yl)-4-(2-methylimidazol-1-yl)pyrimidine; 4-(2-Methylimidazol-1-yl)-6-piperazin-1-ylpyrimidine; 1706446-94-7; UNII-8V7V2V8Q7U; 8V7V2V8Q7U; BDBM50381785; AKOS025147064; ZINC000253949997; A1B1-00796
EINECS	Contact for details

Quality Control

Our 4-(2-Methyl-1H-Imidazol-1-Yl)-6-(Piperazin-1-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.