Description

5-Ethoxy-2,3-difluoro-4-methylbenzaldehyde is a high-purity, multi-functional aromatic aldehyde building block designed for advanced organic synthesis. This compound is valued for its unique substitution pattern, which introduces both fluorine atoms and an ethoxy group onto the benzaldehyde core, enabling precise modulation of electronic and steric properties in target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoro and alkoxy groups contribute to bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for the synthesis of fluorinated aromatic cores used in electronic materials, enhancing properties like charge transport and thermal stability.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent in the development of specialty polymers with tailored optical or surface properties.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies, including cross-coupling reactions and nucleophilic aromatic substitution, facilitated by its fluorine atoms.

Basic Information

Product Name	5-Ethoxy-2,3-difluoro-4-methylbenzaldehyde
CAS No.	1706446-37-8
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2,3-Difluoro-5-ethoxy-4-methylbenzaldehyde; 4-Methyl-2,3-difluoro-5-ethoxybenzaldehyde; Benzaldehyde, 5-ethoxy-2,3-difluoro-4-methyl-; 1706446-37-8
EINECS	Contact for details

Quality Control

Our 5-Ethoxy-2,3-difluoro-4-methylbenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.