Description

4-Fluoro-3-Methyl-2-(Trifluoromethyl)Benzyl Bromide is a high-value, multi-fluorinated benzyl bromide derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both fluorine and trifluoromethyl groups, makes it indispensable for introducing lipophilic and electron-withdrawing motifs into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity, metabolic stability, and membrane permeability.
• Material Science Research: Serves as a precursor for synthesizing specialty monomers, ligands, and functional materials, including liquid crystals and organic semiconductors.
• Fluorine Chemistry: An essential reagent in medicinal and synthetic chemistry for introducing the benzyl bromide functional group in complex, multi-step synthesis under controlled conditions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and process development for client-specific molecules.

Basic Information

Product Name	4-Fluoro-3-Methyl-2-(Trifluoromethyl)Benzyl Bromide
CAS No.	1706438-98-3
Molecular Formula	C9H7BrF4
Molecular Weight	271.05 g/mol
Synonyms	1-(Bromomethyl)-4-fluoro-3-methyl-2-(trifluoromethyl)benzene; (4-Fluoro-3-methyl-2-(trifluoromethyl)phenyl)methyl bromide; α-Bromo-4-fluoro-3-methyl-alpha,alpha,α-trifluoro-o-xylene; 2-(Trifluoromethyl)-4-fluoro-3-methylbenzyl bromide; 4-Fluoro-3-methyl-2-trifluoromethylbenzyl bromide
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We can supply material compliant with ICH guidelines for impurity identification and control to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.