Description

6-Chloro-2,4-Difluoro-3-Methylbenzaldehyde is a high-purity fluorinated benzaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen and aldehyde functional groups, enabling precise molecular construction for complex target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluoromethylbenzene core.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides where the chloro-difluoro pattern enhances biological activity and metabolic stability.
• Material Science Research: Used in creating specialized monomers or ligands for advanced polymers and metal-organic frameworks (MOFs).
• Liquid Crystal & OLED Materials: Intermediate for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Cross-Coupling Reactions: The aldehyde and halogen substituents make it a versatile substrate for Suzuki, Sonogashira, and other palladium-catalyzed couplings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Item	Details
Product Name	6-Chloro-2,4-Difluoro-3-Methylbenzaldehyde
CAS No.	1706435-05-3
Molecular Formula	C8H5ClF2O
Molecular Weight	190.57 g/mol
Synonyms	3-Methyl-6-chloro-2,4-difluorobenzaldehyde; 2,4-Difluoro-6-chloro-3-methylbenzaldehyde; 6-Chloro-2,4-difluoro-3-methyl-benzaldehyde; Benzaldehyde, 6-chloro-2,4-difluoro-3-methyl-; CAS 1706435-05-3
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-2,4-Difluoro-3-Methylbenzaldehyde is produced and tested under a strict quality management system. We ensure high chemical purity and consistency suitable for research and scale-up applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.