Description

2,3-Difluoro-5-Methoxy-4-Methylbenzyl Bromide is a high-purity, multi-functional benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy substituents, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the development of fluorinated drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Material Precursor: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Electronics: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The benzyl bromide moiety acts as an effective electrophile in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Useful for the preparation of fluorinated probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	2,3-Difluoro-5-Methoxy-4-Methylbenzyl Bromide
CAS No.	1706430-78-5
Molecular Formula	C9H9BrF2O
Molecular Weight	251.07 g/mol
Synonyms	4-(Bromomethyl)-2,3-difluoro-5-methoxy-1-methylbenzene; 1-(Bromomethyl)-2,3-difluoro-5-methoxy-4-methylbenzene; 2,3-Difluoro-5-methoxy-4-methylbenzylbromide; 2,3-Difluoro-5-methoxy-4-methylbenzyl bromide; 5-Methoxy-2,3-difluoro-4-methylbenzyl Bromide; (2,3-Difluoro-5-methoxy-4-methylphenyl)methyl Bromide; α-Bromo-2,3-difluoro-5-methoxy-4-methyltoluene
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-5-Methoxy-4-Methylbenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.