Description

3,4-Dichloro-5-(Trifluoromethoxy)Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block. This compound is valued for its unique trifluoromethoxy and dichloro substitution pattern, which imparts significant electronic and steric properties for advanced molecular design. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its structural features make it a critical intermediate for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for improved lipophilicity and bioactivity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its rigid, halogenated aromatic core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	3,4-Dichloro-5-(Trifluoromethoxy)Benzaldehyde
CAS No.	1706430-32-1
Molecular Formula	C8H3Cl2F3O2
Molecular Weight	259.01 g/mol
Synonyms	3,4-Dichloro-5-(trifluoromethoxy)benzaldehyde; 5-(Trifluoromethoxy)-3,4-dichlorobenzaldehyde; Benzaldehyde, 3,4-dichloro-5-(trifluoromethoxy)-; 3,4-Dichloro-α-formyl-5-(trifluoromethoxy)benzene; 3,4-Dichloro-5-(trifluoromethoxy)benzenecarboxaldehyde; CAS 1706430-32-1
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-5-(Trifluoromethoxy)Benzaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.