Description

2-Thiazolepropanoic Acid, β-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (βs)- is a specialized, high-purity building block designed for advanced organic synthesis. This compound matters as a key protected amino acid derivative, enabling the precise construction of complex molecules in research and development. It is primarily needed by pharmaceutical researchers, peptide chemists, and fine chemical manufacturers for applications in drug discovery and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as an Fmoc-protected amino acid derivative for incorporating thiazole-containing amino acids into peptide chains.
• Chemical Biology Research: Employed in the development of peptide-based probes, inhibitors, and tools for studying biological processes and protein-protein interactions.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and organometallic chemistry.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	2-Thiazolepropanoic Acid, β-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (βs)-
CAS No.	1704969-60-7
Molecular Formula	C21H20N2O4S
Molecular Weight	396.46 g/mol
Synonyms	Fmoc-β-(2-thiazolyl)-L-alanine; (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiazol-2-yl)propanoic acid; Fmoc-β-(2-thiazolyl)-Ala-OH; Fmoc-Thz-OH; β-(2-Thiazolyl)-L-alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; N-α-Fmoc-β-(2-thiazolyl)-L-alanine; Fmoc-β-(thiazol-2-yl)-L-alanine; Fmoc-L-β-(2-thiazolyl)alanine
EINECS	Contact for details

Quality Control

Our 2-Thiazolepropanoic Acid, β-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (βs)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) with full specification data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.