Description

3,4-Dichloro-5-Hydroxyphenylboronic Acid is a specialized boronic acid derivative that serves as a crucial building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables efficient cross-coupling reactions, and the chlorinated phenolic structure provides a versatile handle for further derivatization. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker due to its specific reactivity with diols and other functional groups under mild conditions.
• Catalyst Ligand Development: The phenolic and boronic acid functionalities make it a candidate for designing novel ligands in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3,4-Dichloro-5-Hydroxyphenylboronic Acid
CAS No.	1701449-88-8
Molecular Formula	C6H5BCl2O3
Molecular Weight	206.82 g/mol
Synonyms	(3,4-Dichloro-5-hydroxyphenyl)boronic acid; 5-Borono-2,3-dichlorophenol; 2,3-Dichloro-5-boronophenol; B-(3,4-Dichloro-5-hydroxyphenyl)boronic acid; 3,4-Dichloro-5-hydroxybenzeneboronic acid; 1701449-88-8; AKOS026713065
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-5-Hydroxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.