Description

2-Cyclopropyl-6-Fluoroquinazolin-4-Amine CAS NO 1699142-67-0 is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinamine class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its role in the synthesis of novel, targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Used in the development and scale-up of active pharmaceutical ingredients (APIs) targeting specific enzymatic pathways.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and for high-throughput screening.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Cyclopropyl-6-Fluoroquinazolin-4-Amine
CAS No.	1699142-67-0
Molecular Formula	C₁₁H₁₀FN₃
Molecular Weight	203.22 g/mol
Synonyms	6-Fluoro-2-cyclopropylquinazolin-4-amine; 4-Amino-6-fluoro-2-cyclopropylquinazoline; 2-Cyclopropyl-6-fluoro-4-quinazolinamine; 1699142-67-0; 6-Fluoro-2-cyclopropyl-4-quinazolinamine
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-6-Fluoroquinazolin-4-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.