Description

3-Pyridinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-6-Methyl- is a specialized Fmoc-protected amino acid derivative, a critical building block in modern peptide synthesis. This high-purity intermediate is essential for researchers and manufacturers requiring precise control over peptide chain assembly, particularly for introducing modified amino acid residues. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic laboratories engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated, stepwise construction of complex peptide sequences.
• Pharmaceutical Research: Synthesis of active pharmaceutical ingredients (APIs) for peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation & Labeling: Incorporation of a functionalized pyridine moiety into peptides for subsequent conjugation with fluorescent dyes, polymers, or targeting ligands.
• Chemical Biology & Proteomics: Development of enzyme inhibitors, substrate analogs, and activity-based probes to study protein function and interaction.
• Material Science: Synthesis of peptide-polymer hybrids or bio-inspired materials where the specific chemical functionality of this derivative is required.

Basic Information

Product Name	3-Pyridinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-6-Methyl-
CAS No.	1698350-90-1
Molecular Formula	C24H22N2O4
Molecular Weight	402.45 g/mol
Synonyms	Fmoc-6-methyl-3-pyridylalanine; Fmoc-(6-Me-3-Pya)-OH; N-α-Fmoc-6-methyl-3-pyridylalanine; α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-6-methyl-3-pyridinepropanoic acid; Fmoc-3-(6-methylpyridin-3-yl)-L-alanine; Fmoc-β-(6-methyl-3-pyridyl)-L-alanine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-methylpyridin-3-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-Pyridinepropanoic Acid derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept sealed and may require desiccant. For long-term storage, consider storage under an inert atmosphere (argon or nitrogen) to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.