Description

7-Bromo-2,4,6-Trichloro-8-Fluoroquinazoline is a highly functionalized, multi-halogenated quinazoline derivative that serves as a critical advanced intermediate in modern synthetic organic chemistry. Its unique halogen substitution pattern makes it a versatile and valuable building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for its role in facilitating challenging synthetic transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to its reactive bromo and chloro substituents.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Academic & R&D: Utilized in methodological research and discovery chemistry to explore new reaction pathways and create compound libraries for screening.

Basic Information

Item	Detail
Product Name	7-Bromo-2,4,6-Trichloro-8-Fluoroquinazoline
CAS No.	1698028-11-3
Molecular Formula	C8HBrCl3FN2
Molecular Weight	344.36 g/mol
Synonyms	7-Bromo-2,4,6-trichloro-8-fluoroquinazoline; 8-Fluoro-7-bromo-2,4,6-trichloroquinazoline; 2,4,6-Trichloro-7-bromo-8-fluoroquinazoline; Quinazoline, 7-bromo-2,4,6-trichloro-8-fluoro-; BTFQ (abbreviation); 1698028-11-3 (CAS); 7-Br-2,4,6-Cl3-8-F-quinazoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,4,6-Trichloro-8-Fluoroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.