Description

Quinazoline, 7-Bromo-4-Chloro-6,8-Difluoro- CAS NO 1698027-88-1 is a high-purity, multi-halogenated quinazoline derivative, a crucial advanced pharmaceutical intermediate. Its value lies in its complex halogenated structure, which serves as a versatile building block for synthesizing novel, potent bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly in oncology and targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule kinase inhibitors and other targeted cancer therapeutics.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated heterocyclic core.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Research: Investigated as a potential component for organic electronic materials due to its electron-deficient quinazoline structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	Quinazoline, 7-Bromo-4-Chloro-6,8-Difluoro-
CAS No.	1698027-88-1
Molecular Formula	C8H2BrClF2N2
Molecular Weight	287.47 g/mol
Synonyms	7-Bromo-4-chloro-6,8-difluoroquinazoline; 4-Chloro-7-bromo-6,8-difluoroquinazoline; 6,8-Difluoro-7-bromo-4-chloroquinazoline; Quinazoline, 4-chloro-7-bromo-6,8-difluoro-; BOC Sciences Brand Name: BBL-PH-01367; AKOS Brand Name: AKOS005245310; Ambinter Brand Name: Amb27237341; Key Organics Brand Name: 4CH-024329
EINECS	Contact for details

Quality Control

Our Quinazoline, 7-Bromo-4-Chloro-6,8-Difluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.