Description

7-Bromo-6-Chloro-8-Fluoroquinazolin-4-Ol is a high-purity, multi-halogenated quinazolinol derivative serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of novel, targeted therapeutic agents, particularly in oncology and antiviral research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise building block to develop next-generation small molecule drugs and kinase inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for cancer therapy.
• Antiviral Drug Research: Used in the development of new antiviral compounds targeting specific viral enzymes.
• Chemical Biology Probes: Serves as a scaffold for creating selective probes to study cellular signaling pathways.
• Agrochemical Research: Investigated as an intermediate for developing new herbicides and fungicides with novel modes of action.
• Material Science: Potential building block for organic electronic materials due to its halogenated quinazoline core.

Basic Information

Product Name	7-Bromo-6-Chloro-8-Fluoroquinazolin-4-Ol
CAS No.	1698027-18-7
Molecular Formula	C8H3BrClFN2O
Molecular Weight	277.48 g/mol
Synonyms	7-Bromo-6-chloro-8-fluoro-4-quinazolinol; 4-Quinazolinol, 7-bromo-6-chloro-8-fluoro-; 7-Bromo-6-chloro-8-fluoroquinazolin-4(3H)-one; 1698027-18-7; 7-Br-6-Cl-8-F-quinazolin-4-ol; 8-Fluoro-7-bromo-6-chloroquinazolin-4-ol; 6-Chloro-7-bromo-8-fluoro-4-hydroxyquinazoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-6-Chloro-8-Fluoroquinazolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.