Description

6-Bromo-7-Chloro-2-Methylquinazolin-4-Ol is a high-value, multi-functional heterocyclic building block with significant synthetic utility. Its core quinazolinone scaffold, strategically functionalized with bromo and chloro substituents, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive halogen sites.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex quinazolinone motifs.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	6-Bromo-7-Chloro-2-Methylquinazolin-4-Ol
CAS No.	1698026-73-1
Molecular Formula	C9H6BrClN2O
Molecular Weight	273.51 g/mol
Synonyms	6-Bromo-7-chloro-2-methyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 6-bromo-7-chloro-2-methyl-; 6-Bromo-7-chloro-2-methylquinazolin-4(3H)-one; 2-Methyl-6-bromo-7-chloroquinazolin-4-ol; 6-Bromo-7-chloro-2-methyl-3H-quinazolin-4-one; 1698026-73-1
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-Chloro-2-Methylquinazolin-4-Ol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.