Description

Quinazoline, 6-Bromo-4-Chloro-2-Cyclopropyl- is a high-value, multi-substituted heterocyclic building block of significant interest in advanced organic synthesis. Its core quinazoline scaffold, functionalized with bromo, chloro, and cyclopropyl groups, provides versatile handles for further derivatization, making it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its bioactive heterocyclic core.
• Material Science: Acts as a building block for creating specialized organic ligands, dyes, or functional polymers.
• Academic & Contract Research: Employed in medicinal chemistry programs and methodological studies for cross-coupling and functional group transformation reactions.
• Chemical Biology: Utilized as a probe or scaffold for designing molecules that interact with specific biological targets.

Basic Information

Item	Details
Product Name	Quinazoline, 6-Bromo-4-Chloro-2-Cyclopropyl-
CAS No.	1697446-45-9
Molecular Formula	C11H8BrClN2
Molecular Weight	283.55 g/mol
Synonyms	6-Bromo-4-chloro-2-cyclopropylquinazoline; 2-Cyclopropyl-6-bromo-4-chloroquinazoline; 4-Chloro-6-bromo-2-cyclopropylquinazoline; Quinazoline, 4-chloro-6-bromo-2-cyclopropyl-; 1697446-45-9; 6-Bromo-4-chloro-2-cyclopropyl-quinazoline
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-4-Chloro-2-Cyclopropylquinazoline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound should be considered moisture-sensitive (hygroscopic) and handled under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.