Description

4-Bromo-2,3-Difluorobenzyl Chloride is a versatile and highly reactive halogenated benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of bromine, fluorine, and a reactive chloromethyl group on the aromatic ring, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine atoms for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating fluorinated aromatic cores essential in electronic display and lighting technologies.
• Functional Polymer Modification: Employed to introduce halogenated benzyl groups into polymer chains, altering material properties like solubility, thermal stability, and refractive index.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Stille), allowing for further functionalization.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Item	Detail
Product Name	4-Bromo-2,3-Difluorobenzyl Chloride
CAS No.	1691904-69-4
Molecular Formula	C7H4BrClF2
Molecular Weight	241.46 g/mol
Synonyms	1-(Bromomethyl)-2,3-difluoro-4-bromobenzene; (4-Bromo-2,3-difluorophenyl)methyl chloride; 2,3-Difluoro-4-bromobenzyl chloride; α-Chloro-4-bromo-2,3-difluorotoluene; 4-Bromo-2,3-difluoro-α-chlorotoluene; 4-Bromo-2,3-difluorobenzylchloride; 1691904-69-4
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,3-Difluorobenzyl Chloride is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing is performed to guarantee identity, purity, and consistency. A Certificate of Analysis (COA) detailing specific results for purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its reactivity, it should be stored under an inert atmosphere if in opened containers for extended periods.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.