Description

Biotinyl-Amylin (Human) CAS NO 1678415-18-3 is a biotinylated derivative of the human amylin peptide, a key hormone involved in glycemic regulation. This modified form is essential for advanced biochemical research and diagnostic development, offering a stable, high-affinity tag for detection and purification applications. It is primarily utilized by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions focused on metabolic disease studies, diabetes research, and novel therapeutic discovery.

Application

• Biochemical Research Reagent: Used as a critical tool in studying amylin's role in glucose metabolism, insulin secretion, and amyloid formation.
• Diagnostic Assay Development: Serves as a standardized antigen or labeled tracer in the development of immunoassays (ELISA, RIA) for measuring amylin levels.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) platforms and binding studies to identify and characterize potential therapeutics for diabetes and obesity.
• Affinity Purification & Pull-Down Assays: The biotin tag enables efficient isolation of interacting proteins or receptors using streptavidin-coated beads for proteomics research.
• Cell Signaling Studies: Applied in research investigating the downstream signaling pathways and cellular effects mediated by the amylin receptor.
• Quality Control & Standardization: Acts as a reference standard for the quality control of related pharmaceutical peptides and diagnostic reagents.

Basic Information

Product Name	Biotinyl-Amylin (Human)
CAS No.	1678415-18-3
Molecular Formula	C164H267N51O50S2
Molecular Weight	~3905.4 g/mol
Synonyms	Biotinylated Human Amylin; Biotin-Amylin (Human); Biotinyl-Islet Amyloid Polypeptide (IAPP); Biotin-LC-Amylin (1-37), human; Biotinylated Diabetes-Associated Peptide; Biotin-IAPP; Biotinyl-KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2; Biotin-AC-Amylin
EINECS	Contact for details

Quality Control

Our Biotinyl-Amylin (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. For specific purity grades or custom QC requirements, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Molecular Weight	3905.4 ± 2.0 Da (by MS)
Water Content (K.F.)	≤ 5.0%
Solubility	Soluble in water, DMSO, or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.