Description

Tau Peptide (273-284) CAS NO 1663490-91-2 is a synthetic peptide fragment corresponding to amino acid residues 273-284 of the human tau protein. This specific sequence is of significant interest in neurological research, particularly for studying tauopathies such as Alzheimer's disease. It serves as a critical research tool for antibody development, epitope mapping, and investigating protein aggregation mechanisms. Researchers in pharmaceutical R&D, academic neuroscience, and diagnostic development utilize this high-purity peptide for advanced biochemical studies.

Application

• Neuroscience Research: Fundamental studies on tau protein function, misfolding, and aggregation pathology.
• Antibody Production & Validation: Immunogen for generating and characterizing tau-specific monoclonal and polyclonal antibodies.
• Diagnostic Assay Development: Key component in ELISA, Western blot, and other immunoassays for detecting tau-related biomarkers.
• Epitope Mapping: Precisely defining antibody binding sites within the tau protein sequence.
• Drug Discovery Screening: Target peptide for high-throughput screening of compounds designed to inhibit abnormal tau aggregation.
• Biochemical Standard: Use as a reference standard in quantitative protein analysis and quality control for related reagents.

Basic Information

Product Name	Tau Peptide (273-284)
CAS No.	1663490-91-2
Molecular Formula	C₆₀H₉₉N₁₉O₁₈
Molecular Weight	1354.5 g/mol
Synonyms	Tau (273-284); Tau Protein Fragment (273-284); hTau (273-284); Microtubule-associated protein tau (273-284); MAPT (273-284); Peptide tau 273-284; Tau peptide sequence VQIINK; Human tau peptide residues 273-284
EINECS	Contact for details

Quality Control

Every batch of Tau Peptide (273-284) is manufactured under strict quality management and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for critical research applications, with purity typically exceeding 95% as determined by HPLC. Certificates of Analysis (COA) detailing batch-specific results for identity, assay, purity, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Amino Acid Composition	Conforms to theoretical values
Molecular Weight (MS)	1354.5 ± 2 Da
Peptide Content	≥ 70%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.