Description

Fmoc-L-Lys[Oct-(Otbu)-Glu-(Otbu)-Aeea-Aeea]-Oh is a sophisticated, multi-functional peptide building block designed for advanced solid-phase peptide synthesis (SPPS). This compound is engineered to facilitate the efficient construction of complex peptide-drug conjugates (PDCs) and bioconjugates, offering precise control over molecular architecture. It is an essential reagent for researchers and manufacturers in the pharmaceutical and biotechnology sectors who are developing targeted therapeutics, including antibody-drug conjugates (ADCs) and other innovative biopharmaceuticals.

Application

• Peptide-Drug Conjugate (PDC) Synthesis: A critical intermediate for constructing the linker-payload segment of novel PDCs, enabling targeted drug delivery.
• Antibody-Drug Conjugate (ADC) Development: Used to create bespoke, cleavable linker systems that connect cytotoxic agents to monoclonal antibodies.
• Solid-Phase Peptide Synthesis (SPPS): Serves as a specialized Fmoc-protected amino acid derivative for the sequential assembly of complex, branched, or labeled peptide sequences.
• Bioconjugation and Labeling: Facilitates the site-specific attachment of drugs, fluorophores, or other functional moieties to peptides, proteins, or other biomolecules.
• Prodrug Design: Employed in the development of peptide-based prodrugs where controlled release of the active pharmaceutical ingredient is required.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new modalities in targeted cancer therapy and diagnostic imaging.

Basic Information

Item	Detail
Product Name	Fmoc-L-Lys[Oct-(Otbu)-Glu-(Otbu)-Aeea-Aeea]-Oh
CAS No.	1662688-20-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Lys(Oct-Glu(OtBu)-Aeea-Aeea)-OH; Fmoc-L-Lysine[8-amino-3,6-dioxaoctanoic acid-5-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(tert-butoxy)-5-oxopentanoic acid-8-amino-3,6-dioxaoctanoic acid]; Fmoc-Lys(Oct-Glu(OtBu)-AEEA-AEEA)-OH; Fmoc-L-Lys(Oct-Glu(OtBu)-AEEA-AEEA)-OH; Fmoc-Lysine(Oct-Glutamic acid(OtBu)-AEEA-AEEA)-OH; ADC/Linker Building Block 1662688-20-1; SPPS Reagent 1662688-20-1
EINECS	Contact for details

Quality Control

Every batch of Fmoc-L-Lys[Oct-(Otbu)-Glu-(Otbu)-Aeea-Aeea]-Oh is produced and tested under strict quality management systems. We employ advanced analytical techniques, including HPLC and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.