Description

(4-Chloropyrimidin-2-Yl)Methanamine Hydrochloride is a high-purity, pharmaceutically relevant chemical building block. This compound is a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapeutics. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors and other targeted cancer therapies.
• Agrochemical Research: Used in the development of novel herbicides and fungicides.
• Chemical Biology: Serves as a versatile scaffold for probe and tool compound development in drug discovery.
• Organic Synthesis: A valuable precursor for constructing complex heterocyclic compounds in medicinal chemistry.
• Contract Manufacturing (CMO/CDMO): Supplied to organizations for cGMP and non-GMP scale-up synthesis.
• Academic Research: Utilized in university and institutional labs for novel synthetic methodology and biological activity studies.

Basic Information

Product Name	(4-Chloropyrimidin-2-Yl)Methanamine Hydrochloride
CAS No.	1646556-93-5
Molecular Formula	C5H7Cl2N3
Molecular Weight	180.04 g/mol
Synonyms	2-(Aminomethyl)-4-chloropyrimidine hydrochloride; 1-(4-Chloropyrimidin-2-yl)methanamine hydrochloride; 4-Chloro-2-pyrimidinemethanamine hydrochloride; (4-Chloro-2-pyrimidinyl)methylamine hydrochloride; 4-Chloro-2-(aminomethyl)pyrimidine hydrochloride; 2-(Aminomethyl)-4-chloro-pyrimidine HCl
EINECS	Contact for details

Quality Control

Our (4-Chloropyrimidin-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP development and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.