Description

Fmoc-Methr(Me)-Oh CAS NO 1645308-94-6 is a high-purity, protected amino acid derivative specifically engineered for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over stereochemistry and side-chain functionality during solid-phase and solution-phase peptide assembly. It is an essential building block for pharmaceutical R&D, particularly in the development of novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the sequential construction of complex peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and development of peptide-based drugs targeting various diseases.
• Peptidomimetic Design: Incorporates modified amino acid structures to enhance metabolic stability and bioavailability of drug candidates.
• Combinatorial Chemistry Libraries: Serves as a versatile scaffold for generating diverse compound libraries for high-throughput screening.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for diagnostic or therapeutic applications.
• Academic & Institutional Research: Supports fundamental studies in biochemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Fmoc-Methr(Me)-Oh
CAS No.	1645308-94-6
Molecular Formula	C21H23NO5
Molecular Weight	369.41 g/mol
Synonyms	Fmoc-N-methyl-threonine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine; Fmoc-N-Me-Thr-OH; (2S,3R)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl(methyl)amino]-3-hydroxybutanoic acid; Fmoc-N-methylthreonine; N-Fmoc-N-methyl-L-threonine; Fmoc-N-Me-Threonine-OH; Protected N-methyl-threonine derivative
EINECS	Contact for details

Quality Control

Our Fmoc-Methr(Me)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.