Description

(S)-3-(4-Phenoxyphenyl)-1-(Piperidin-3-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted kinase inhibitors and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard or active compound in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Drug Discovery: Serves as a core scaffold for medicinal chemists to develop new chemical entities (NCEs) with potential therapeutic applications.
• Preclinical Development: Employed in the production of compounds for pharmacological profiling, pharmacokinetic studies, and toxicology assessments.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Academic Research: Utilized in university and institutional labs for fundamental studies in chemical biology and medicinal chemistry.

Basic Information

Product Name	(S)-3-(4-Phenoxyphenyl)-1-(Piperidin-3-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	1642571-07-0
Molecular Formula	C22H22N6O
Molecular Weight	386.45 g/mol
Synonyms	(S)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-1-(3-piperidinyl)-, (S)-; (S)-1-(Piperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; UNII-9V8P7J8Q4F; 9V8P7J8Q4F; CHEMBL3186665; BDBM50166653; AKOS025147394
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for pharmaceutical development. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from comprehensive analytical methods including HPLC, NMR, and mass spectrometry. We support development projects with quality documentation that meets the standards expected in pre-clinical and early-phase clinical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider sealing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.