Description

(E)-Methyl 3-(3,5-Difluoro-4-Formylphenyl)Acrylate CAS NO 1639042-39-9 is a high-purity fluorinated aromatic acrylate derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the strategic combination of a reactive acrylate ester and a formyl group on a difluorinated benzene ring, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small molecule drugs, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, leveraging the fluorine atoms for enhanced bioavailability and stability.
• Material Science Research: Serves as a monomer or cross-linker precursor in the development of specialty polymers with tailored optical or surface properties.
• Ligand and Catalyst Development: The formyl and acrylate functionalities make it a versatile precursor for synthesizing complex chelating ligands and organocatalysts.
• Fluorescent Probe & Dye Synthesis: The conjugated system provides a foundation for creating fluorophores and molecular probes used in diagnostics and bioimaging.

Basic Information

Product Name	(E)-Methyl 3-(3,5-Difluoro-4-Formylphenyl)Acrylate
CAS No.	1639042-39-9
Molecular Formula	C11H8F2O3
Molecular Weight	226.18 g/mol
Synonyms	Methyl (2E)-3-(3,5-difluoro-4-formylphenyl)-2-propenoate; (E)-Methyl 3-(3,5-difluoro-4-formylphenyl)acrylate; 2-Propenoic acid, 3-(3,5-difluoro-4-formylphenyl)-, methyl ester, (2E)-; Methyl (E)-3-(3,5-difluoro-4-formylphenyl)acrylate; 3,5-Difluoro-4-formylcinnamic acid methyl ester; MFCD30566616; 1639042-39-9
EINECS	Contact for details

Quality Control

Our production of (E)-Methyl 3-(3,5-Difluoro-4-Formylphenyl)Acrylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.