Description

2,4-Dichloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This heterocyclic compound serves as a critical building block for the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is essential for research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the development of novel oncology and anti-inflammatory treatments.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of small molecule kinase inhibitors and other targeted therapies.
• Oncology Drug Development: Used in research and production of active pharmaceutical ingredients (APIs) for cancer treatment candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant API synthesis.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Item	Detail
Product Name	2,4-Dichloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid Methyl Ester
CAS No.	1638771-51-3
Molecular Formula	C11H9Cl2N3O2
Molecular Weight	286.11 g/mol
Synonyms	Methyl 2,4-dichloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate; 2,4-Dichloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid methyl ester; 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 2,4-dichloro-7-methyl-, methyl ester; 1638771-51-3; Pyrrolopyrimidine methyl ester derivative
EINECS	Contact for details

Quality Control

Our production of 2,4-Dichloro-7-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.